Komedieserien Girlfriends tager et kig på fire forskellige kvinders liv, kærlighed og tab: Toni, Maya, Lynn og Joan.
Just before Mother’s Day, Maya is disturbed when her mother announces she’s selling the house and moving to San Bernardino with her boyfriend. Toni has issues when her mother shows up unannounced for Mother’s Day and continually embarrasses her.
S2E20 21 min